From July 15–18, 2025, the 4th Joint Meeting on Environmental Chemistry and Substances (33rd Environmental Chemistry Symposium / 29th Annual Meeting of the Japanese Society of Environmental Toxicology) was held in Yamagata City.
Our laboratory attended with three presenters (faculty and students)!

This year’s theme was:
“One Health Approaches in Environmental Chemistry and Toxicology: Solutions for Health Challenges Shaped by Humans, Animals, Environment, and Society.”

A perfect fit for our lab’s mission:
Integrating environmental toxicology with next-generation technologies!

Our Presentations

We delivered three presentations, including two oral presentations and one poster.

✅ TH-B1-6

Development of an In Silico Target Protein Prediction Method via Comprehensive Molecular Docking on the AlphaFold-Predicted Protein Structure Proteome: A Case Study on Puberulic Acid
Presenter: Teppei Hayama (Ph.D. student)
Format: Oral + Poster

Leveraging the power of AlphaFold structure proteome and Binding Proteomics, this study comprehensively explored binding candidates of puberulic acid, proposing a novel strategy for toxicity target prediction.

✅ WE-C2-1

Evaluation of Testicular Toxicity in Mice Exposed to a Nine-Compound Mixture of Linear Perfluoroalkyl Substances at Human Daily-Intake-Equivalent Levels
Presenter: Wakana Yoshimura (6th-year student)
Format: Oral Presentation

We conducted a mixture exposure study simulating human-relevant PFAS intake and evaluated its impact on male mouse testes—addressing the hot topic of reproductive toxicity risk at low PFAS concentrations.

✅ SP-091

Rodenticidal Effect and Mechanistic Study of Dcha-20, a Novel Lithocholic Acid Derivative with a Unique Mode of Action
Presenter: Misaki Fukamatsu (6th-year student)
Format: Poster Presentation

This research analyzed the rodenticidal activity and toxicity mechanisms of Dcha-20, a compound designed as a vitamin D receptor agonist, contributing to the development of eco-friendly rodenticides.

Conference Highlights

This year’s joint meeting featured:

• Integration of Environmental Chemistry and Toxicology

• One Health-based problem solving

• Risk assessment using next-generation technologies

It was truly an ideal platform for showcasing our lab’s strengths.
Although Dr. Takeda did not present this time, he was busy serving as a session chair and organizing committee member, making this a very active and productive four days for our team!

Breaking News!!

We are thrilled to announce that...
ALL THREE STUDENT PRESENTERS WON AWARDS!!!
Yes, an incredible 100% success rate! 🎉
Details will be featured in a separate post—stay tuned!