Publications

Domestic conference

2023

• "Exploration of In Vivo Factors Contributing to Differences in Pharmacokinetics between cis-trans Isomers of Anti-Coagulant Rodenticides"
  Moyu Miyamae, Satoru Nagaoka, Sanae Yamamoto, Ryo Kamata, Kazuki Takeda
  The 50h Annual Meeting of the Japanese Society of Toxicology (2023).

  • URL
• "Exploratory Research of Toxicity Assessment Using Protein Structure Prediction by AlphaFold2"
  武田一貴
  The 50th Annual Meeting of the Japanese Society of Toxicology (2023).

  • URL

  Invited Presentation; Frontier Seminar
• "Evaluation of Rodenticide Susceptibility of the Natural Monument; Bonin Flying Fox using AlphaFold2 and Molecular Simulation"
  Kazuki Takeda, Yusuke K Kawai, Nobuaki Yasuo, Masakazu Sekijima, Kodai Manago, Yoshinori Ikenaka, Kazuo Horikoshi, Hajime Suzuki, Mayumi Ishizuka, Shouta MM Nakayama
  第2回環境化学物質3学会合同大会 (2023).

  • URL
• "Application of cultured cells obtained from green sea turtles for evaluation of toxicity test with anticoagulant rodenticides."
  Masafumi Katayama, Tomoichi Fukuda, Kazuki Takeda, Satomi Kondo, Toru Kiyono, Shouta Nakayama
  Japanese Geoscience Union Meeting 2023 (2023).

  • URL
• "Evaluation of Subchronic Toxicological Effects of Low Concentration Mixed Exposure of Nine Linear PFAS on Mice"
  Kazuki Takeda, Taki Saito, Sakura Sasaki, Akifumi Eguchi, Ryo Kamata
  6th International Chemical Hazard Symposium (2023).

  • URL

2022

• "Highly Accurate Protein Structure Prediction Using AlphaFold2 for Toxicity Assessment ～Environmental Pollutants as an Application Case Study～"
  Kazuki Takeda
  The 5th Study Group on Toxicological Mechanisms of Pharmaceuticals (2022).

  • URL

  Nominating Symposium: off-target toxicity target exploration
• "2022 年に捕獲した小笠原諸島父島の外来クマネズミにおける殺鼠剤ダイ ファシノンの薬物動態‧薬力学（PK/PD）解析による感受性評価"
  清水 敬太, 佐藤 美侑, 片山 雅史, 中山 翔太, 池中 良徳, 一瀬貴大, 石塚 真由美, 鎌田 亮, 小山田 佑輔, 港 隆一, 橋本 琢磨, 田中 和之, 谷川 力, 武田 一貴
  第28回日本野生動物医学会大会 (2022).

  • URL

  最優秀賞受賞
• "小笠原諸島の外来クマネズミに対する抗血液凝固系殺鼠剤ダイファシノンの薬物動態・薬力学(PK/PD)解析による感受性評価"
  清水 敬太, 佐藤 美侑, 片山 雅史, 中山 翔太, 池中 良徳, 一瀬貴大, 石塚 真由美, 鎌田 亮, 小山田 佑輔, 港 隆一, 橋本 琢磨, 武田 一貴
  第165回日本獣医学会学術集会 (2022).

  • URL

  優秀発表賞（野生動物分科会）受賞
• "インク由来化学物質群のゼブラフィッシュ胚への芳香族炭化水素受容体(AhR)を介する毒性影響評価"
  更田 葵依, 武田 一貴, 清水 敬太, 寺崎 正紀, 鎌田 亮
  第165回日本獣医学会学術集会 (2022).
• "Gazing at the risk of anticoagulant rodenticides (ARs) application from aquatic biota: Attempt to evaluate ARs toxicity in sea turtles"
  Yoshiya Yamamura, Chiyo Kitayama, Satomi Kondo, Kazuki Takeda, Takahiro Ichise, Yoshinori Ikenaka, Mayumi Ishizuka, Shouta M.M. Nakayama
  The 49th Annual Meeting of the Japanese Society of Toxicology (2022).

  Symposium (nominated): On the frontline of wildlife toxicity assessment by young researchers
• "Construction of a method for predicting animal species differences in chemical sensitivity from human single nucleotide polymorphisms using molecular simulation"
  Kazuki Takeda, Nobuaki Yasuo, Masakazu Sekijima
  The 49th Annual Meeting of the Japanese Society of Toxicology (2022).

  Symposium (nominated): On the frontline of wildlife toxicity assessment by young researchers
• "Characterization of Clotting Factor IX Transcript variant 2 by cultured cells assay and Alphafold2"
  Kanami Watanabe, Ryo Sato, Ryo Kamata, and Kazuki Takeda
  The 49th Annual Meeting of the Japanese Society of Toxicology (2022).
• "Evaluation of Toxicological Effects of Low Concentration Mixed Exposure of Perfluoroalkyl Substances (PFASs) on Mice"
  Kazuki Takeda, Taki Saito, Sakura Sasaki, Akifumi Eguchi, Ryo Kamata
  Joint Conference on Environmental Chemicals (2022).
• "Evaluation of Aromatic Hydrocarbon Receptor (AhR) Agonistic Activity of Sensitizer-Related Compounds Using Zebrafish"
  更田 葵依、武田 一貴、清水 敬太、寺崎 正紀、鎌田 亮
  Joint Conference on Environmental Chemicals (2022).

  SETAC Award
• "Development of resources for assessing the effects of pollutants on green sea turtles"
  Masafumi Katayama; Tomokazu Fukuda; Manabu Onuma; Kazuki Takeda; Satomi Kondo; Shouta MM Nakayama
  Japan Geoscience Union Meeting 2022 (2022).

  • URL
• "環境汚染物質による細胞内受容体作用と生物影響の検出"
  鎌田 亮
  岩手大学ソフトパス理工学総合研究センター環境科学・工学研究グループ勉強会 (2022).
• "Functional analysis of splicing variant 2 of blood coagulation factor IX"
  Kanami Watanabe, Ryo Sato, Ryo Kamata, and Kazuki Takeda
  The 4th Spring Meeting of the Japanese Society of Comparative Pharmacology and Toxicology (2022).
• "Characterization of Clotting Factor IX Transcript variant 2"
  Kanami Watanabe, Ryo Sato, Ryo Kamata, and Kazuki Takeda
  5th International Chemical Hazard Symposium (2022).

2021

• "惹起相を有する皮膚感作性試験開発のためのマウスにおける感作性物質曝露と感作反応の検証"
  鎌田 亮, 中村 和市, 武田 一貴
  第164回日本獣医学会学術集会 (2021).
• "Estimating susceptibility of rodenticide by molecular dynamics & machine learning using 3D structure of vitamin K epoxide reductase"
  Kazuki Takeda, Nobuaki Yasuo, Kanami Watanabe, Ryo Sato, Ryo Kamata, Masakazu Sekijima
  29th Symposium on Environmental Chemistry Royal Society of Chemistry Award (2021).

  • URL

  Royal Society of Chemistry Award